UniProt Release 2024_02 The UniProt consortium European Bioinformatics Institute (EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource (PIR), is pleased to announce UniProt Knowledgebase (UniProtKB) Release 2024_02 (27-Mar-2024). UniProt (Universal Protein Resource) is a comprehensive catalog of information on proteins. UniProtKB Release 2024_02 consists of 248,805,733 entries (UniProtKB/Swiss-Prot: 571,282 entries and UniProtKB/TrEMBL: 248,234,451 entries) UniRef100 Release 2024_02 consists of 398,132,654 entries UniRef90 Release 2024_02 consists of 187,136,236 entries UniRef50 Release 2024_02 consists of 64,363,428 entries UniParc Release 2024_02 consists of 737,125,415 entries, where 679,391,852 are active and 57,733,563 inactive UniProt databases can be accessed from the web at http://www.uniprot.org and downloaded from http://www.uniprot.org/downloads. Detailed release statistics for TrEMBL and Swiss-Prot sections of the UniProt Knowledgebase can be viewed at http://www.ebi.ac.uk/uniprot/TrEMBLstats/ and http://web.expasy.org/docs/relnotes/relstat.html respectively.